Beta blockers reduce heart rate with reduction of strength of contraction also. If channel blocker Ivabradine is a novel drug. Coronary blood flow maintained. Myocardial oxygen demand reduced. Sensation of brightness in the fully illuminated field is the adverse event.
A brief review of the drug Is available in the below link.
http://www.jyoungpharm.in/downloadpdf.asp?issn=0975-1483;year=2009;volume=1;issue=3;spage=284;epage=284;aulast=Ameya;type=2
Hope this information is useful.
Dr. Shiva Murthy N
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